Free Biochemistry MCQ on Amino acid and Nitrogen Metabolism is available for you on medicalfond.
1.
It
is an one of the cell organelle which contain lytic enzymes and used for
degradation of macromolecules
A.
Mitochondria
B.
cell membrane
C.
cytosol
D.
endoplasmic recticulum
2.
All
of the following are physiological buffers except
A.
Bicarbonate B. phosphate C. amino acid acetic acid D.HB is an acid
3.
It
is a major intracellular buffer
A.
Bicarbonate B. phosphate C. amino acid D.
acetic acid
4.
Metabolic
alkalosis is due to
A. a
decrease in carbonic acid
B.an increase in bicarbonate
C. a
decrease in bicarbonate
D.
an increase in carbonic acid.
5.
One
of the following is negatively charged (acidic ) amino acid
A.
lysine B. arginine C. histidine D.glutamate E. all
6.
If a
protein is made up of more than one polypeptide chain it is said to have
A.
primary structure
B. Secondary
structure
C.
tertiary structure
D.
quaternary structure
7.
All
of the following are true about transamination reaction except one
A.
is reversible ,occurs in all the tissues
B.
Concentrates nitrogen in glutamate for oxidative deamination that liberates
free NH3 for urea synthesis
C. require PLP (derived from Vit. B6) as
coenzyme
D.
all aa participate in transamination
E.
It diverts excess aa towards energy generation
8.
The
removal of amino group from the amino acid as NH3 is termed as
A.
transamination
B.
deamination
C.
Transdeamination
D.
oxidation reduction
9.
Glutamate
is an inhibitory neurotransmitter
A.
True B. False
10.
The
transporter forms of ammonia from peripheral tissues to liver is/ are
A.
glutamate B. glutamine C.alanine D.
all
11.
The
Linkage between Urea Cycle and Citric Acid Cycle
A.
malate B. oxaloacetate C.aspartate D. fumarate
12.
The
end product of protein metabolism is/ are
A.
ammonia B. urea C. amino acid D.CO2
13.
A
major class of enzyme which concerned with ad of carbon which is an elimination
reaction
A. Transferases
B.
Hydrolases
C. Lyases
D.
Ligases
14.
The
carbon atoms of acetyl-CoA
A.
are lost as Co, molecules.
B.
are recycled with oxaloacetate.
C
play no role in the reaction.
D
are donated to succinate dehydrogenase.
15.
Isocitrate
dehydrogenase is considered a regulatory enzyme in the citric
A.
its activity is inhibited by the presence of citrate.
B.
its activity is inhibited by the presence of ADP.
C.
its activity is inhibited by the presence of high-energy compounds.
D.
its activity is regulated by cofactors produced in the cycle.
16.
Identify
the wrong statement about regulation of fatty acids synthesis,
A
Citrate increase the rate of fatty acids synthesis
B.
Long chain fatty acids decrease rate of fatty acids synthesis
C.
Insulin stimulate fatty acids synthesis
D.
Glucagon inhibit the rate of fatty acids oxidation
17.
In
Citric Acid cycle substrate level phosphorylation occur at steps catalyzed by:
A.
Succinate thiokinase
B.
Isocitrate dehydrogenase
C.
Succinate dehydrogenase
D.
a-ketoglutrate dehydrogenase
18.
The
citric acid cycle
A.
uses eight enzymes and the final product is malate.
B.
uses eight enzymes and the final product is oxaloacetate.
C
results in the production of 1 ATP molecule.
D.
results in the production of 2 ATP molecules
19.
The
carbon atoms of acetyl-CoA
A.
are lost as CO2 molecules
B.
are recycled with oxaloacetate,
C.
play no role in the reaction.
D.
are donated to succinate dehydrogenase.
20.
The
final intermediate product in the citric acid cycle is
A.
L-malate
B.
Acetyl-CoA.
C.
Oxaloacetate.
D.
Fumarate
21.
GTP
is synthesized in the citic acid cycle
A.
in the transformation of succnyl-CoA to succinate.
B.
in the transformation of succinate to fumarate.
C.
in the transformation of succinate to succinyl-CoA.
D.
GTP is not synthesized in the citric acid cycle, 1 molecule of ATPIS
22.
Isocitrate
dehydrogenase
A.
is activated by high concentrations of ATP and NADH.
B.
is activated by high concentrations of ATP and NADPH.
C.
is unaffected by high concertations of NADPH.
D. is
inhibited by high concentrations of high-energy compounds,
E.
None of the above
23.
Glucokinase
A.
used by skeletal muscle to initiate glycolysis.
B.
is used by the liver and has a low affinity for glucose
C.
is used by the liver, and has a high affinity for glucose.
D.
is not an isozyme of hexokinase.
24.
The
initial investment of ATP required in glycolysis is
A. 4
ATP molecules.
B. 2
ATP molecules.
C. 1
ATP molecule.
D.
No ATP is required.
25.
In
the pay-off phase of glycolysis, the total number of ATP molecues produced is
A.
1.
C.4.
D.
6.
26.
Degradation
of proteins into carbohydrates
A.
requires proteases
B.
requires deamination
C is
oxidative
D.
in some cases created intermediates that feed directly into the TC cycle.
E.
All of the above
27.
In
the urea cycle, the first amide group to enter the cycle
A.
enters as ammonium ion.
B.
is activated by attachment of a phosphate from the cleavage of ATP.
C.
is provided by aspartate.
D.
forms ornithine.
28.
The
linkage between urea cycle and krebs cycle is through
A.
aspartate
B.
fumarate
C.
oxaloacetate
D. glutamate