1)
Which
of the following step is common in the glycolysis and pentose phosphate
pathway?
a) Conversion of glucose to
glucose-6-P
b) Conversion of glucose-6-P to
ribose-5-P
c) Conversion of glucose-6-P- to
fructose-6-P
d) Conversion of glucose to
glucose-1-P
2)
Pentose
phosphate pathway is responsible for generating NADPH (reducing equivalents in
the cell) in the cell.
Which of the following enzyme is
involved in generating NADPH?
a) Glucose-6-P oxidase
b) Glucose-6-P dehydrogenase
c) Glucose-6-P reductase
d) Glucose-6-P synthetase
3)
Which
of the following step is the rate-limiting step of the pentose phosphate
pathway?
a) Transketolase
b) Glucose-6-P dehydrogenase
c) Transaldolase
d) Phosphogluconate dehydrogenase
4)
Insulin
activates the pentose phosphate pathway.
Which of the following enzyme is
activated by insulin action?
a) Transketolase
b) Glucose-6-P dehydrogenase
c) Transaldolase
d) Phosphogluconate dehydrogenase
5)
Which
of the following enzyme is used for the diagnosis of thiamine deficiency?
a) Transketolase
b) Glucose-6-P dehydrogenase
c) Transaldolase
d) Phosphogluconate dehydrogenase
6)
Glucose
-6-Phosphate dehydrogenase is allosterically activated by
a) NADPH
b) NADH
c) NAD +
d) NADP +
7)
Glucose-6-Phosphate
dehydrogenase is allosterically inhibited by
a) Acetyl CoA
b) Citrate
c) Glucose
d) Fructose
8)
In
some individuals, ingesting fava beans leads to hemolytic anemia.
Which of the following enzyme may be
deficient in these individuals?
a) Glucose-6-Phosphatase
b) Glucose-6-P- dehydrogenase
c) Glucose -6-Phosphate Isomerase
d) Glycogen phosphorylase
9)
What
is the cause of hemolytic anemia in Glucose-6-phosphate deficiency?
a) Decreased ATP in erythrocytes
b) Decreased free radicals in
erythrocytes
c) Increased sodium concentration in
erythrocytes
d) Increased free radicals in
erythrocytes
10)
The
glutathione cycle is the conversion of oxidized glutathione to reduced
glutathione in the presence of NADPH.
Which of the following enzyme
catalyzes this reaction?
a) Glutathione peroxidase
b) Glutathione dehydrogenase
c) Glutathione reductase
d) Glutathione synthetase
11)
What
is the enzyme responsible for the breakdown of triglycerides into fatty acids
and mono-acylglycerol in the intestine?
a) Pancreatic lipase
b) Lipoprotein lipase
c) Hormone-sensitive lipase
d) Phospholipase
12)
What
is the function of bile salt in the intestine?
a) Activator of lipase
b) Emulsifier
c) Co-factor for cholesteryl
esterase
d) Inhibitor of lipid absorption
13)
What
is the precursor for bile salt synthesis?
a) Fatty acid
b) Glucose
c) Cholesterol
d) Glycerol
14)
The
anti-obesity drug Orlistat inhibits
a) Pancreatic lipase
b) Lipoprotein lipase
c) Hormone-sensitive lipase
d) Phospholipase
15)
Which
of the following class of fatty acids can be directly absorbed from the intestine?
a) Very long-chain fatty acid
b) Long-chain fatty acid
c) Short-chain fatty acid
d) Cholesterol esters
16)
The
lipid digestion process is regulated by different local hormones.
The cholecystokinin hormone released
from....
a) Mucosa of the jejunum
b) Pancreatic delta cells
c) Gastric Parietal cells
d) Pancreatic alpha cells
17)
Which
of the following is not the effect of cholecystokinin released from mucosal
cells of the jejunum?
a) Contraction of gall bladder and
release of bile acids
b) Release of digestive enzymes from
the exocrine pancreas
c) The slower release of gastric
content into the stomach
d) Increased gastric motility
18)
Lack
of appropriate lipid absorption leads to a condition known as..................................
a) Metabolic syndrome
b) Obesity
c) Fatty liver
d) Steatorrhea
Answers
1- a, 2-b, 3-b, 4-b, 5-a,
6-d, 7-b, 8-b, 9-d, 10-c
11-a) Pancreatic Lipase
12-b) Emulsifier
13-c) Cholesterol
14- Pancreatic Lipase
15-c) Short-chain fatty acid
16-a) Mucosa of the jejunum
17-c) The slower release of gastric
content into the stomach
18-d) Steatorrhea